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anthrax infection clearlyexplained.com

clearlyexplained

16th October 2001

by Richard Conan-Davies BSc Dip Ed

A straightforward and fast information
guide to anthrax infection from
ClearlyExplained.Com

updated:20 October 2005

 

Original images of anthrax taken by Robert Koch (1843-1910)


Nature of anthrax infection
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Technology/treatment
of anthrax infection
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The | What | Why | News | How | History | Future | of anthrax infection

What is anthrax infection?

This is a condition caused by a bacteria Bacillus anthracis that usually causes infections with herd animals.

The infection in humans is also called woolsorters disease (see history also).

Reference: oxford concise medical dictionary


Where does the word Anthrax come from?

Anthrax is the greek word for coal, it probably gets this name from appearance of the skin form of the infection that produced pustules that tend to produce a blackish colour.

( Compare with the geological mineral Anthracite which is a form of coal)

 

The bacteria typically infects either

  • The lungs, causing a form of pneumonia,
  • The skin.
  • It sometimes infects the intestines. But this is rather rare.

Most occupational cases are skin infections.

source:

 

To see images of skin anthrax infections have a look at Anthrax Images on www.dermatlas.com from the John Hopkins Medical Institute.

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Disclaimer:

Although every care has been taken to make this site useful,
this site does not provide anthrax treatment advice.
You should consult a qualified medical officer or doctor for anthrax infection advice specific to you.


Why is anthrax infection important?

Anthrax is currently of interest due to the world terrorism issues.

As an infective agent it is a concern because it forms very resistant spores that can be transported easily.

 

The university of Tasmania provides interesting highlights to its use in bio warfare.

The disease is also of significance to the farming industry. It is sometimes more of a problem in the developing world but occasionally occurs in the developed.

 

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News about anthrax infection.

newsanthrax infection issues are frequently reported in the news. Here are some of the best sources of the latest news about anthrax infection.

 

Tip: please bookmark or favourite
this page for quick access to these handy sources

Updated Daily!
Nature & Science News
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Some reliable and quality assured sources of general information about anthrax infection include:

Australia:

US:

Canada

UK/Europe:

International

WHO biological warfare

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How is anthrax infection studied?

anthrax infection can be classified in various ways.

Nature of anthrax infection
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This covers the basic biology and linked with anthrax infection

Treatment of anthrax infection
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This is the practical application of science to help treat anthrax infection, including treatments.

The infection is typically treated by massive doses of antibiotics.

Typically this is penicillin G or streptomycin.

updated:

Currently the antibiotic of choice is Ciprofloxacin hydrochloride . Here is the FDA FAQ on it

 

A vaccine could be used for prevention.

Vaccines
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How does the infection occur?

Anthrax can be infective if between 8,000- 50,000 spores are inhaled.

Here are examples of bacteria turning into spores, these are called endospores at this stage.

Typically the spores are inhaled and can develop into bacteria , that then infect the many small air sacs in the lung. This tends to be the most dangerous form.

Skin infections by anthrax are less severe and a more easily treated.

updated:

Anthrax produces toxins that act like enzymes. The toxins (called exotoxins) are made from 3 separate proteins that are controlled by a bacterial plasmid ( a small ring of DNA).

 

However, the university of Wisconsin provides some useful insights into Anthrax, which includes some good advice on not worrying too much.

Scientific American has a useful article in relation to how the infection works


Reference: Prescot L.M, Harley, J.P et al (1993) Microbiology second edition. Wm.C. Brown Publishers

 

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What is the history of anthrax infection?

 

kochAnthrax was one of the first diseases to be analysed and isolated by Robert Koch (1843 - 1910), the founder of modern microbiological techniques.

 

 

The disease anthrax has been around for as long as animals, mammals in particular.

The early days it is was an occupational hazard of working with livestock, as spores would develop and get stuck in the wool/skin of animals. The workers often got skin infections and sometimes inhaled if they were in a closed environment.

 

The disease was also investigated by John Bell, a British doctor in the mid 1800s who noticed the relationship between anthrax and woolsorters disease.

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The future of anthrax infection?

The main focus of the future of anthrax is developing a vaccine for its prevention.

Eurka Alert: Bacillus anthracis search provides some of the very latest research findings.

 

 

Here are some examples of the kind of research related to anthrax vaccines

  • The Cochrane institute provides a study for anthrax vaccine
  • Ohio State University with study for anthrax vaccine

    The (US) National Institute of Allergy and Infectious Disease
    provides links to studies on Anthrax.

 

     

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Why

News

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Disclaimer:

Although every care has been taken to make this site useful, this site does not provide anthrax infection advice. You should consult your doctor for anthrax infection advice specific to you.

 

 

About the Author

Richard, has worked explaining science for the past 10 years, including at Questacon, Mount Stromlo, CSIRO, the Maritime Museum in Greenwich, and various schools in South East London. He studied immunology and biochemistry at ANU.


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